Hydrogen-Rich Water Ameliorates Autistic-Like Behavioral Abnormalities in Valproic Acid-Treated Adolescent Mice Offspring
نویسندگان
چکیده
منابع مشابه
Autism-like behaviours with transient histone hyperacetylation in mice treated prenatally with valproic acid.
Maternal use of valproic acid (VPA) during pregnancy has been implicated in the aetiology of autism spectrum disorders in children, and rodents prenatally exposed to VPA showed behavioural alterations similar to those observed in humans with autism. However, the exact mechanism for VPA-induced behavioural alterations is not known. To study this point, we examined the effects of prenatal exposur...
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In-utero exposure to valproic acid (VPA) has been known as a potent inducer of autism spectrum disorder (ASD), not only in humans, but also in animals. In addition to the defects in communication and social interaction as well as repetitive behaviors, ASD patients usually suffer from gastrointestinal (GI) problems. However, the exact mechanism underlying these disorders is not known. In this st...
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ژورنال
عنوان ژورنال: Frontiers in Behavioral Neuroscience
سال: 2018
ISSN: 1662-5153
DOI: 10.3389/fnbeh.2018.00170